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Additionally, the indole Main is substituted at R3 having a carbonyl group that's also bonded into a napthalene moeity. Napthalene can be a bicyclic framework of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it being a ketone. JWH-018 is really an analog of THJ-018, by which the core indazole construction is substituted with the indole base. Pharmacology

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